Completely or partially funded by grants R01LM009886 and 3OT3-TR002027-01S1.

Name	Authors	Status	Link to demo or license	Description
Chia	Fabrício Kury, Alex Butler, Chi Yuan, Li-heng Fu, Yingcheng Sun, Hao Liu, Ida Sim, Simona Carini & Chunhua WengFabrício Kury, Alex Butler, Chi Yuan, Li-heng Fu, Yingcheng Sun, Hao Liu, Ida Sim, Simona Carini, Chunhua Weng	Open-source	Source code	Chia, a novel, large annotated corpus of patient eligibility criteria extracted from 1,000 interventional, Phase IV clinical trials registered in ClinicalTrials.gov. This dataset includes 12,409 annotated eligibility criteria, represented by 41,487 distinctive entities of 15 entity types and 25,017 relationships of 12 relationship types.
PICO Parser	Tian Kang, Chunhua Weng	Open-source	Source code	A scalable deep learning method to extract PICO statements from RCT articles.
COVID-19 Trial Finder	Alex Butler, Yingcheng Sun, Fengyang Lin, Hao Liu, Cong Liu, Chi Yuan, Chunhua Weng	Open-source	Demo Source code	A simplified method for patients, clinicians and healthy volunteers to search for appropriate COVID-related clinical trials in their general location. This system also allows potential candidates to pre-screen their eligibility for such trials through a set of short medical questions. Check out the news
Criteria2Query	Yilu Fang, Yingcheng Sun, Hao Liu, Chi Yuan, Patrick Ryan, Yixuan Guo, Chunhua Weng	Open-source	Demo Source code	A system for transforming free-text eligibility criteria into structured database queries for identifying eligible patients from clinical databases.
Doc2HPO	Cong Liu, Chunhua Weng	Open-source	Source code
COHD	Casey Ta, Nick Tatonetti, George Hripcsak, Chunhua Weng	Open-source	URL API API source code	Columbia Open Health Data (COHD). COHD provides public access to observational prevalence rates and co-occurrence frequencies of conditions, drugs, procedures, and demographics measured from electronic health records from 5M+ patients in the CUMC’s OHDSI database.
SNOMEDTxT	Olga Lyudovyk, Chunhua Weng	Open-source	Demo Source code	It is built with SNOMED CT US Snapshot version. SNOMED CT files were downloaded and pre-processed before they could be used in this project.
EliXR-CDM	Gal Fix, Anil Yaman, Chunhua Weng	Prototype		The winner of the 2015 AMIA Joint Summit for Clinical Research Informatics Design Challenge
EliIE	Tian Kang, Chunhua Weng	Prototype		A machine learning based parser for clinical research eligibility criteria
Valx	Tony Hao, Chunhua Weng	Prototype	Source code	A parser for numeric expressions in clinical trial summaries.
VITTA	Zhe He, Riccardo Miotto, Tony Hao, Ida Sim, Simona Carini, Chunhua Weng	Prototype		A visualization system of aggregated patterns of clinical trial eligibility criteria
eTACTS	Riccardo Miotto, Chunhua Weng	Prototype; Open-source	Source code	Search engine for clinical trials allowing users to refine the results of an initial search through cloud of tags automatically extracted from the eligibility criteria.
AQUA	Stephen Johnson, David Campbell, Eneida Mendonca, Robert Duffy, Chunhua Weng	License available	#2943 (freely available)	An dependency parser for biomedical text Patent Status: Software Copyright
BBW Prediction	Handong Ma, Chunhua Weng	Linked clinical trials and drug adverse events data	Code	Link public data resources for predicting post-marketing drug safety label changes by analyzing the Convergent Focus Shift patterns among drug testing trials.
Questionable Criteria	Handong Ma, Chunhua Weng	Questionable Criteria and Disease Facts	Code	A method for identifying questionable exclusion criteria for 38 mental disorders.

Completely or partially funded by grant UL1TR001873 and 1OT2TR003434-01.

Name	Authors	Status	Link to demo or license	Description
CTKB	Hao Liu, Yuan Chi, Alex Butler, Yingcheng Sun , Chunhua Weng	Open-source	URL	Clinical Trial Knowledge Base, a regularly updated knowledge base of discrete clinical trial eligibility criteria equipped with a web-based user interface for querying and aggregate analysis of common eligibility criteria.

Completely or partially funded by grant R01LM010815.

Name	Authors	Status	Link to demo or license	Description
IMPACT	Yat So, J Thomas Bigger, Linda Busacca, Carlos Lopez, Richard Steinman, Chunhua Weng	In use at CTSA of CUIMC	CU license	A research scheduling and resource allocation software.