During the early-1970s, for my doctoral dissertation, I was principal developer of the clinical expert system known as MYCIN. After a pause for internal medicine house-staff training at Harvard and Stanford between 1976 and 1979, I joined the Stanford internal medicine faculty where I directed a research program in biomedical informatics. My interests include the broad range of issues related to integrated decision-support systems and their effective implementation. In the early 1980s, I worked to create the Stanford degree program in biomedical informatics. From 1995-1999, I served as Associate Dean for Information Resources and Technology at Stanford University School of Medicine. I then moved to Columbia University, where I have served as Professor and Chair of the Department of Biomedical Informatics since January 2000.

My publications through the end of the 1990s are summarized on the Stanford Medical Informatics site. More recent publications are available on the DBMI site. Other details are available in my Curriculum Vitae. Books include:

• Computer-Based Medical Consultations: MYCIN (Elsevier/North Holland, 1976)
• Readings in Medical Artificial Intelligence: the First Decade (with W.J. Clancey; Addison-Wesley, 1984)
• Rule-Based Expert Systems: The MYCIN Experiments of the Stanford Heuristic Programming Project (with B.G. Buchanan; Addison-Wesley, 1984).
• Medical Informatics: Computer Applications in Health Care and Biomedicine (with L.E. Perreault, G. Wiederhold, and L.M. Fagan; Addison-Wesley, 1990; second edition, Springer Verlag, 2000).
• Biomedical Informatics: Computer Applications in Health Care and Biomedicine (with J.J. Cimino); third edition, Springer Verlag, 2006).